Gene: Lrp3 ENSMUSG00000001802

Description

low density lipoprotein receptor-related protein 3 [Source:MGI Symbol;Acc:MGI:3584516]

Location

Chromosome 7: 34,899,194-34,915,139 reverse strand.

GRCm39:CM001000.3

About this gene

This gene has 31 transcripts (splice variants), 188 orthologues, 15 paralogues and is associated with 6 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000122409.8	Lrp3-202	4147	790aa	ENSMUSP00000114026.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS52202	E9Q1T6	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000485684.1	Lrp3-206	5136	634aa	ENSMUSP00000264047.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENSMUST00000485701.1	Lrp3-223	4258	827aa	ENSMUSP00000264064.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENSMUST00000485695.1	Lrp3-217	4139	642aa	ENSMUSP00000264058.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding		-	A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic,
ENSMUST00000118444.4	Lrp3-201	4084	769aa	ENSMUSP00000113406.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		E9Q711	GENCODE Primary represents a minimal set that contains MANE Select, MANE Plus Clinical and Ensembl Canonical transcripts and transcripts containing any conserved exons and common alternative splicing events (including exons skips) that are absent from the MANE and Ensembl Canonical transcripts for protein-coding genes. Other biotypes will have the GENCODE Primary flag added to the Ensembl Canonical transcript and for lncRNA genes only this will be the transcripts with the longest genomic span.GENCODE Primary, A subset of the GENCODE transcript set, containing only 5' and 3' complete transcripts at protein-coding genes.GENCODE Basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 5: A transcript where no single transcript supports the model structure. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:5,
ENSMUST00000485686.1	Lrp3-208	4307	81aa	ENSMUSP00000264049.1	Nonsense mediated decay		-	-
ENSMUST00000485687.1	Lrp3-209	4228	85aa	ENSMUSP00000264050.1	Nonsense mediated decay		-	-
ENSMUST00000485709.1	Lrp3-231	4206	100aa	ENSMUSP00000264072.1	Nonsense mediated decay		-	-
ENSMUST00000485685.1	Lrp3-207	4176	488aa	ENSMUSP00000264048.1	Nonsense mediated decay		-	-
ENSMUST00000485694.1	Lrp3-216	4166	75aa	ENSMUSP00000264057.1	Nonsense mediated decay		-	-
ENSMUST00000485703.1	Lrp3-225	4166	93aa	ENSMUSP00000264066.1	Nonsense mediated decay		-	-
ENSMUST00000485696.1	Lrp3-218	4113	220aa	ENSMUSP00000264059.1	Nonsense mediated decay		-	-
ENSMUST00000485706.1	Lrp3-228	4099	79aa	ENSMUSP00000264069.1	Nonsense mediated decay		-	-
ENSMUST00000485699.1	Lrp3-221	4070	290aa	ENSMUSP00000264062.1	Nonsense mediated decay		-	-
ENSMUST00000485691.1	Lrp3-213	4040	188aa	ENSMUSP00000264054.1	Nonsense mediated decay		-	-
ENSMUST00000485689.1	Lrp3-211	4039	100aa	ENSMUSP00000264052.1	Nonsense mediated decay		-	-
ENSMUST00000485688.1	Lrp3-210	4037	43aa	ENSMUSP00000264051.1	Nonsense mediated decay		-	-
ENSMUST00000485707.1	Lrp3-229	4030	94aa	ENSMUSP00000264070.1	Nonsense mediated decay		-	-
ENSMUST00000485700.1	Lrp3-222	4027	77aa	ENSMUSP00000264063.1	Nonsense mediated decay		-	-
ENSMUST00000485702.1	Lrp3-224	4011	115aa	ENSMUSP00000264065.1	Nonsense mediated decay		-	-
ENSMUST00000485690.1	Lrp3-212	4000	56aa	ENSMUSP00000264053.1	Nonsense mediated decay		-	-
ENSMUST00000485704.1	Lrp3-226	3958	553aa	ENSMUSP00000264067.1	Nonsense mediated decay		-	-
ENSMUST00000485697.1	Lrp3-219	3947	79aa	ENSMUSP00000264060.1	Nonsense mediated decay		-	-
ENSMUST00000485683.1	Lrp3-205	3927	790aa	ENSMUSP00000264046.1	Nonsense mediated decay	CCDS52202	-	-
ENSMUST00000485693.1	Lrp3-215	3915	64aa	ENSMUSP00000264056.1	Nonsense mediated decay		-	-
ENSMUST00000485705.1	Lrp3-227	3894	528aa	ENSMUSP00000264068.1	Nonsense mediated decay		-	-
ENSMUST00000485708.1	Lrp3-230	3883	532aa	ENSMUSP00000264071.1	Nonsense mediated decay		-	-
ENSMUST00000485692.1	Lrp3-214	3772	467aa	ENSMUSP00000264055.1	Nonsense mediated decay		-	-
ENSMUST00000485698.1	Lrp3-220	2957	202aa	ENSMUSP00000264061.1	Nonsense mediated decay		-	-
ENSMUST00000153163.2	Lrp3-203	420	No protein	-	Alternatively spliced transcript of a protein coding gene for which we cannot define a CDS.Protein coding CDS not defined		-	TSL 5: A transcript where no single transcript supports the model structure. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:5,
ENSMUST00000155404.3	Lrp3-204	2089	No protein	-	An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron		-	TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,

Gene: Lrp3 ENSMUSG00000001802

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Gene: Lrp3 ENSMUSG00000001802

Summary

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